Cratched tablets number 20

Kratal (CRATAL) instruction manual

Composition

active ingredients: 1 tablet contains hawthorn fruit thick extract (Crataegiae fructus extractum spissum) (3.0-3.3: 1), (extractant: ethanol 70% v / v), in terms of dry matter - 43 mg, wasteland extract thick (Leonhuriae herba extractum spissum) (4,5-5,6: 1), (extractant: ethanol 70% v / v), in terms of dry substance - 87 mg, taurine, in terms of 100% dry matter - 867 mg
auxiliary substances: microcrystalline cellulose, sodium croscarmellose, magnesium stearate, silicon dioxide colloidal.

Dosage form

Pills.

Basic physical and chemical properties:

oval tablets from light gray or light brown to dark brown, with interspersed, chamfered.

Pharmacological group

Cardiologic means. ATX Code C01E X.

Pharmacological properties

Pharmacodynamics.

Kratal has soft cardiotonic, antianginal, antioxidant, antiarrhythmic, antihypoxic, antiaggregant and antiatherogenic effects; inhibits the renin-angiotensin and kallikrein-kinin system, processes of lipid peroxidation, positively influences the production of cAMP. It improves the blood supply and functional state of the myocardium, increases the "coronary reserve", improves the contractile and pumping functions of the heart muscle, reduces blood pressure and normalizes the heart rate.

Kratal reduces signs of digital intoxication. Increases working capacity, improves mood, renders calming, neuroprotective action (eliminates somatonegative disorders - irritability, mood changes).

Pharmacokinetics.

The components of the drug are almost completely absorbed from the digestive tract. The time for which the maximum concentration of taurine and other components of the drug in the blood is reached is 2:00. Kratal is evenly distributed in the tissues and fluids of the body. The main amount of it is excreted in the urine, the half-life period is 6-8 hours.

Indications

• Cardiopsychoneurosis;
• in combination therapy with:
• chronic ischemic heart disease;
• post-radiation syndrome.

Contraindications

Hypersensitivity to the drug components
bradycardia and arterial hypotension are expressed.

Interaction with other drugs and other interactions

Potentiates antianginal effects of nitrates, β-adrenoblockers, calcium antagonists, antihypoxants, neuroprotectors, cardiac glycosides. Reduces signs of digital intoxication. Do not use the drug with antiarrhythmic drugs III class, cisapride.

Application features

Do not exceed the recommended dose of the drug.

If during the treatment the symptoms do not disappear or worsen, you should consult a doctor.

If there is swelling of the ankles or legs, when there is pain in the heart, which can spread to the left arm, upper abdomen or neck area, or if dyspnoea appears, immediately consult a doctor.

Use during pregnancy or lactation.

Until now, there is no data on the use of the drug during pregnancy and lactation.

The drug is contraindicated for use during pregnancy.

If you need to take the drug during breastfeeding, during treatment, breast-feeding should be discontinued.

The ability to influence the reaction rate when driving vehicles or other mechanisms.

For the period of treatment, patients who take Cratal should refrain from managing vehicles and potentially dangerous mechanisms.

Dosing and Administration

Duration of treatment and dose are determined individually. The drug is administered orally 1-2 tablets 3 times daily before meals. The course of treatment is 3-4 weeks.

Children

The experience of the drug in children is not.

Overdose

Symptoms: hypersensitivity reactions, allergic reactions, dyspeptic reactions, general weakness, fatigue, dizziness, drowsiness, arterial hypotension, bradycardia.

Treatment: withdrawal of the drug and symptomatic therapy.

Adverse Reactions

Possible manifestations of hypersensitivity, allergic reactions (including hyperemia, rash, itching, swelling of the skin, urticaria), dyspepsia, general weakness, fatigue, dizziness, drowsiness, arterial hypotension, bradycardia.

In case of occurrence of any undesirable phenomena the patient should consult a doctor.

Shelf life

3 years. Do not use after the expiration date stated on the package.

Storage conditions

In the original packaging at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Packaging

For 10 tablets in a blister, 2 blisters per pack; 60 tablets per container; 60 tablets in a container and a pack; 90 tablets in a container; 90 tablets in a container and a pack.

Category of leave

Without recipe.