Preparations for tachycardia

This section presents the main medicines used to normalize the heart rhythm. The reasons for the development of tachycardia may be different, but sometimes, in addition to eliminating them, the use of appropriate medications is required. If suitable treatment is not carried out, various complications can arise with all the ensuing consequences. When tachycardia is defined, the […]

This section presents the main medicines used to normalize the heart rhythm. The reasons for the development of tachycardia may be different, but sometimes, in addition to eliminating them, the use of appropriate medications is required. If suitable treatment is not carried out, various complications can arise with all the ensuing consequences.

When tachycardia is defined, the heart rate is higher than 90 beats per minute (normal in adults 60-90 beats / min). In children, normal heart rate may be higher, so each case is treated individually, taking into account the age of the child.

Often and long-term tachycardia can lead to worsening of the heart, increased blood pressure and poor blood filling of cerebral vessels. To prevent such consequences, appropriate therapy should be carried out, usually with the use of antiarrhythmic drugs.

Video: Medications for tachycardia

Preparations for the treatment of tachycardia

Treatment depends on the severity of tachycardia and the presence of major or concomitant diseases.

  • Vagal tests. Certain physical actions stimulate the vagus nerve, which by its influence on the sinus node slows the heart rate. For example, the Valsalva test (forced exhalation with a closed nose and mouth) can slow down some types of tachycardia.
  • Medications.
    • Antiarrhythmic drugs are used to eliminate abnormal heart rhythms and abnormal heart activity.
    • Treatment with anticoagulants is necessary for those patients who have atrial fibrillation or an increased risk of blood clots and stroke.
  • Catheter ablation. Catheters are inserted through the blood vessels in the heart to cauterize or freeze the myocardium and destroy (ablation) abnormal ways of carrying out. Ablation is commonly used to treat Wolff-Parkinson-White syndrome, atrial fibrillation and atrial flutter.
  • Cardioversion . Correctly selected force of an electric current (synchronously with heart), at influence through a thorax, allows to restore a normal heart rhythm. The most common indications for this procedure are atrial fibrillation, atrial flutter and supraventricular tachycardia.
  • Urgent asynchronous defibrillation. This mode of action is similar to cardioversion, except that the procedure more quickly provides higher energy discharges in an attempt to prevent the development of life-threatening arrhythmias.
  • Implantation of a cardioverter-defibrillator. The device is implanted on a permanent place in the chest for the purpose of continuous monitoring of cardiac activity. If an irregular rhythm is detected, the device immediately generates an electric current to restore normal cardiac activity. Indication for implantation is severe heart failure with a high risk of developing life-threatening arrhythmias.
  • Operation "Maze-procedure" During the implementation of this surgical intervention, abnormal electrical pathways in the heart are destroyed. Such an operation is performed when other treatment options are ineffective.

Prevention

Some forms of tachycardia can be avoided by controlling risk factors, which primarily include a lifestyle that often leads to cardiovascular disease. Also, recommendations for preventing tachycardia include smoking cessation, increased sleep and rest time, avoidance of alcohol and drug abuse.

Essential preparations for tachycardia

Tachycardia, which usually develops at a heart rate of more than 100 beats / min, can be the result of various cardiac pathologies. The first step in choosing the right drug is to determine the origin of the arrhythmia. Most tachycardias are classified according to ECG-indicators into two types:

  1. Narrow-QRS-complex tachycardias (eg, atrial fibrillation, atrial flutter, atrial or multifocal atrial tachycardia)
  2. Widely-QRS-complex tachycardias (eg, ventricular tachycardia or supraventricular tachycardia with aberrantness).

Each type requires appropriate treatment. In narrow-QRS-complex tachycardia with a regular heart rate, the following are commonly used:

  • Adenosine
  • Beta-blockers
  • Calcium channel blockers
  • Amiodarone
  • Ibutilide

In tachycardia with a wide QRS-complex, the first step in arresting an attack is to determine the type of arrhythmia: ventricular tachycardia or tachycardia with aberrantence. Widely-QRS-complex tachycardias with aberrantity give in to the same therapy as narrow-QRS-complex tachycardias. Severely flowing ventricular tachycardia with frequent impulses is treated only with amiodarone or amiodarone in combination with synchronous cardioversion.

Adenosine (Adenosinum)

This antiarrhythmic drug is used primarily as a diagnostic tool to identify the origin of tachycardia with narrow QRS-complexes.

The drug shortens the activity of the atrioventricular (AV) and sinus node for a short time. When the agent is administered bolus, its primary action is to slow the electropulse conductivity through the AV node. Because of this, adenosine usually causes a few seconds of asystole, but because of its short half-life (6 to 10 seconds), asystole usually occurs briefly.

The medicine sometimes helps restore a normal sinus rhythm. If it is ineffective, calcium channel blockers and beta-blockers can be immediately administered to monitor heart rate. Other drugs like amiodarone or ibutilide can be used to restore normal sinus rhythm.

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Diltiazemum

The first line device for controlling heart rate in narrow QRS-complex tachycardias. This drug can be used both in patients with preserved cardiac function, and in the presence of impaired ventricular function (ejection fraction below 40%) or heart failure. (Verapamil, another calcium channel blocker, should be used only in patients with preserved cardiac function).

Being a blocker of calcium channels, diltiazem slows down and / or blocks electrical impulse conductivity through the AV node. With its help, the number of impulses entering the ventricles decreases, and the heart rate slows down.

Use of the drug may cause secondary hypotension due to relaxation of smooth muscle vessels. In addition, the drug can block impulses for some tachycardia with a narrow QRS complex, which are associated with the re-activation of the AV node. As a result, the rhythm slows down and normal cardiac activity is restored.

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Other drugs

Sometimes, some beta-blockers are used to control the heart rate associated with a narrow-QRS-complex tachycardia.These include:

  • Metoprolol
  • Atenolol
  • Propranolol
  • Esmolol.

Propranolol is not a cardioselective adrenoblocker, so it can additionally affect pulmonary function. For this reason, it is used less often. Esmolol, as a rule, is used in extreme cases.

Atenolol is administered at a dose of 5 mg bolus for 5 minutes. If the patient normally takes the medicine, and the arrhythmia persists after 10 minutes, an additional bolus is administered at a dose of 5 mg for 5 minutes.

Metoprolol is also administered bolus in 5 mg increments for 5 minutes. The dose can be reused twice, up to 15 mg.

It is not necessary to use beta-blockers or calcium channel blockers in patients with tachycardia and narrow QRS-complexes, with suspicion of impaired conduction by the type of Wolff-Parkinson-White syndrome (WPW). Such arrhythmias allow impulses to spread from the atria to the ventricles through additional ways of carrying out. Beta-blockers and calcium channel blockers can increase the number of impulses entering the ventricles, which in turn will accelerate the heart rate.

Amiodarone

This drug is used to treat certain tachycardias with narrow and wide QRS, identified as ventricular tachycardia or tachycardia of unknown origin.

Despite the fact that amiodarone belongs to antiarrhythmic drugs of the third class, it has some properties of all antiarrhythmic classes. Its primary action is to block the potassium channels in the cell, but it also prolongs the duration of the action potential, slows the conduction rate and prolongs refractoriness in the AV node. In addition, it blocks alpha, beta and calcium channels.

Dosage depends on the patient's condition. When used to treat ventricular tachycardia, an attack of paroxysmal ventricular tachycardia or a narrow-QRS-complex tachycardia, amiodarone is administered as a bolus of 150 mg for 10 minutes. Then a continuous infusion is started, starting at 1 mg / min for 6 hours, and then 0.5 mg / min for 18 hours. If the patient's condition is stable for a long time, the infusion can be continued at a rate of 0.5 mg / min. Otherwise, an oral dose is prescribed, which usually begins before the end of the infusion.

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Drugs for sinoatrial tachycardia

If episodes of rhythm disturbance are rare or they are easily removed by increasing the tone of the vagus nerve, medical therapy is not performed.

Intensive treatment may be required in the following cases:

  • Episodes of sinoatrial tachycardia occur frequently
  • Attacks of rhythm disturbance are difficult to eliminate by vagal tests

Drug therapy is quite effective in severe cases. After assessing the general condition of the patient, doctors are usually appointed:

  • Beta-blockers
    • Anaprilin
    • Metoprolol
    • Bisoprolol
    • Labetalol
    • Talinolol
  • Calcium channel blockers
    • Verapamil
    • Gallopamil
    • Diltiazem

With the help of these drugs, it is possible to significantly reduce the severity of episodes of tachycardia and / or alleviate the condition of the patient.

If the sinus tachycardia is especially difficult to flow and does not respond to drug therapy, ablation is prescribed. Today, this method is considered effective and able to completely relieve arrhythmia. Nevertheless, it is difficult to remove the additional electrical pathway in the sinus node without damaging the rest of the formation, so sometimes ablation does not justify waiting.

There are suggestions that the procedure of ablation has a rather high risk of significant sinus bradycardia. Sometimes it has such a degree of severity that a permanent pacemaker may be required. Therefore, attempts to find non-invasive therapy are always paramount before we have to treat catheter ablation.

Drugs with supraventricular tachycardia

A fast heart rhythm can develop with interruptions and in such cases it is rarely dangerous for life. Episodes of tachycardia usually begin with additional early cardiac contractions. Although these extraordinary strokes occur in all children and adults, their frequency can be increased through the use of caffeine and other stimulants (eg, medications to treat bronchial asthma). For this reason, people with supraventricular tachycardia (SVT) are often advised to avoid the use of caffeine and certain medications.

Attacks SVT can be stopped by vagal (vagal) assays. Vagal's tests stimulate the vagus nerve, which is directed to the heart from the central brain. This technique for the elimination of tachycardia includes:

  1. Inflation of the thumb, as if it is a ball (without the passage of air during inflation)
  2. Tightening of the abdomen, as if during a defecation
  3. Put the face in ice water or apply ice to the cheeks, forehead, further holding your breath.

Learn how to use these methods of arresting an attack of tachycardia can adults and older children themselves. Very young children are helped to eliminate the attack of tachycardia by upside down and holding in this position for up to 5 seconds.

If vagal tests do not work, and the episode lasts longer than 45 minutes, the patient should be provided with emergency medical care. Usually an antiarrhythmic drug of the IV class called adenosine is prescribed, which helps to bring the heart rate back to normal. If the attack can not be remedied medication, serious electrical symptoms may require electrical cardioversion.

Treatment of SPT more often includes:

  • Careful observation using vagal specimens
  • Medication effect
  • Radiofrequency ablation.

Decisions about the tactics of treatment are made on the basis of:

  • Age of the patient
  • Frequency and severity of symptoms
  • Efficiency of use of medical products
  • Presence of desire, especially for a child, to participate in sports
  • Preferences of the child / family.

Table 1. Comparative data between the main drugs from supraventricular tachycardia according to drugs.com

Preparations Tradename Class of antiarrhythmic drugs Dosage Efficiency rating on a 10-point scale Pregnancy Alcohol
Metoprolol Metoprolol Succinate ER, Toprol-XL, Lopressor Cardioselective beta-blocker 50 mg; 100 mg; 25 mg; 200 mg; 37.5 mg; 75 mg 6.0 Risk is not excluded Interacts with alcohol
Atenolol Tenormin Cardioselective beta-blocker 50 mg; 100 mg; 25 mg; 0.5 mg / ml 7.0 Positive evidence of risk Interacts with alcohol
Verapamil Calan SR, Calan, Verelan, Verelan PM, Covera-HS, Isoptin SR 4 class, calcium channel blockers 180 mg / 24 hours; 120 mg / 24 hours; 240 mg / 24 hours; 360 mg / 24 hours; 2.5 mg / ml; 40 mg; 80 mg; 120 mg; 240 mg / 12 hours;120 mg / 12 hours; 180 mg / 12 hours; 100 mg / 24 hours; 200 mg / 24 hours; 300 mg / 24 hours 6.0 Risk is not excluded Interacts with alcohol
Diltiazem - 4 class, calcium channel blockers 30 mg; 60 mg; 90 mg; 120 mg; 5 mg / ml; 120 mg / 24 hours; 180 mg / 24 hours; 240 mg / 24 hours; 300 mg / 24 hours; 360 mg / 24 hours; 420 mg / 24 hours; 100 mg; 60 mg / 12 hours; 90 mg / 12 hours; 120 mg / 12 hours; 25 mg; 125 mg / 125 ml-D5%; 250 mg / 250 ml-D5%; 100 mg / 100 ml-D5%; 100 mg / 100 ml-NaCl 0.9%;125 mg / 125 ml-NaCl 0.9% 7.0 Risk is not excluded -
Bisoprolol - Cardioselective beta-blocker 5 mg; 10 mg 5.0 Risk is not excluded Interacts with alcohol
Amiodarone Cordarone, Pacerone, Nexterone Grade 3 50 mg / ml; 200 mg; 300 mg; 100 mg; 400 mg; 150 mg / 100 ml; 900 mg / 500 ml; 450 mg / 250 ml; 360 mg / 200 ml 5.0 There are risk data -
Adenosine Adenocard, Adenoscan 4th grade - 7.0 Risk is not excluded -
Flecainide Tambocor 1 class 50 mg; 100 mg; 150 mg 4.0 Risk is not excluded -
Nadolol Corgard Non-selective beta-blockers 40 mg; 120 mg; 20 mg; 80 mg; 160 mg 9.0 Risk is not excluded Interacts with alcohol
Phenylephrine - Vasopressors, decongestants 10 mg / ml; 2.5 mg; 10 mg; 1.25 mg / 0.8 ml; 5 mg / 5 ml; 50 mg / 250 ml-NaCl 0.9%; 100 μg / ml-NaCl 0.9%; 0.8 mg / 10 ml-NaCl 0.9%; 40 mg / 250 ml-NaCl 0.9%; 200 μg / 5 ml-NaCl 0.9%; 2.5 mg / 5 ml; 80 μg / ml-NaCl 0.9%; 20 mg / 250 ml-NaCl 0.9%; 10 mg / 250 ml-NaCl 0.9%; 10 mg / 5 ml; 25 mg / 250 ml-NaCl 0.9%; 30 mg / 250 ml-NaCl 0.9%; 20 mg / 50 ml-NaCl 0.9%; 40 mg / 250 ml-D5%; 0.4 mg / 10 ml-NaCl 0.9%; tannate 10 mg; tannate 7.5 mg / 5 ml; 400 μg / 10 ml-NaCl 0.9%; 7.5 mg / 5 ml - Risk is not excluded -
Propranolol Inderal 2 class, unselective beta-blocker 60 mg; 10 mg; 20 mg; 40 mg; 80 mg; 120 mg; 160 mg; 1 mg / ml;20 mg / 5 ml; 80 mg / ml; 40 mg / 5 ml; 4.28 mg / ml 7.0 Risk is not excluded Interacts with alcohol

 Preparations for ventricular tachycardia

Treatment will depend on the manifestations of the disease. It may not be required at all if:

  • There are no cardiac pathologies
  • No severe or severe symptoms
  • Episodes of tachycardia last not for long

If symptoms are identified that the doctor may deem unfavorable, the appropriate medicine may be prescribed:

  • Beta-blocker
  • Potassium channel blockers
  • Antiarrhythmics of 1st class (flecainide)
  • Local injection anesthetic (lidocaine)
  • Antidiuretic hormonal drug (vasopressin)

Ventricular tachycardia (VT), which is chronic or life-threatening, can be treated by implantation of a cardioverter of a defibrillator. This small device is installed in the chest and connected to the heart by wires. When an abnormal heartbeat occurs, the device sends electrical signals, which allows you to restore normal heartbeat. But sometimes even using a cardioverter-defibrillator, you have to take beta-blockers, amiodarone or sotalol.

Some VT can be treated with catheter ablation. This procedure is based on the use of radio frequency charge to destroy abnormal heart tissue, which causes rapid heartbeat.

If there is a high risk of sudden death from VT, it is prescribed:

  • Beta-blocker
  • ACE inhibitor
  • Spironolactone
  • Polyunsaturated fatty acids

Amiodarone and sotalol can also prevent unwanted and unsafe early cardiac contractions.

Common problems and side effects of using medicines:

  • Drugs are very difficult to take on a regular basis. Antiarrhythmic drugs, if they are effective, should not be missed in their reception. It is important to know that antiarrhythmics can be proarrhythmic, and in such cases they worsen the flow of arrhythmia.
  • Fleckainide and propafenone can provoke a resistant VT, and sotalol is able to cause prileent tachycardia (torsade de pointes).
  • Beta-blockers are very effective, but they have a number of side effects, such as symptomatic bradycardia, cardiac blockade and fatigue.
  • Amiodarone has numerous side effects, such as toxic effects on the liver, thyroid and lungs, but it can suppress cardioverter-defibrillator strokes that often worsen the quality of life.

Medication control of concomitant diseases

Diabetes - statins, ACE inhibitors and angiotensin II receptor blockers are very useful and can positively influence the course of this disease.

Hypertension - ACE inhibitors, angiotensin II receptor blockers, beta blockers are preferred, especially in patients with renal insufficiency and after MI and / or heart failure

There are certain restrictions regarding the intake of compulsory medicines:

  • Non-selective beta-blockers should be avoided in patients with bronchospasm.
  • Aspirin is not recommended for patients with a high risk of bleeding.
  • Spironolaton - in renal failure, ACE inhibitors and angiotensin II receptor blockers in acute renal failure.
  • Calcium channel blockers - with systolic heart failure.

In addition, the following recommendations should be adhered to:

  • Stop smoking.
  • Drink alcohol in moderation. Excess alcohol can be toxic to the myocardium and often provokes cardiac arrhythmias (especially atrial fibrillation).
  • Narcotic substances, such as cocaine, can provoke an acute coronary syndrome with coronary artery vasospasm.
  • Excessive use of caffeine in some susceptible patients can initiate atrial fibrillation.
  • It is necessary to limit calories in excess weight.
  • Use the practice for the mood of emotional balance.

Table 2. Comparative data between the main drugs from ventricular tachycardia according to drugs.com

Preparations Tradename Class of antiarrhythmic drugs Dosage Efficiency rating on a 10-point scale Pregnancy Alcohol
Atenolol Tenormin Cardioselective beta-blocker 50 mg; 100 mg; 25 mg; 0.5 mg / ml 8.0 Confirmed evidence of risk to the fetus Interacts with alcohol
Amiodarone Cordarone, Pacerone, Nexterone Grade 3 50 mg / ml; 200 mg; 300 mg; 100 mg; 400 mg; 150 mg / 100 ml; 900 mg / 500 ml; 450 mg / 250 ml; 360 mg / 200 ml 5.0 There is evidence of risk to the fetus -
Propranolol Inderal, Inderal LA, Hemangeol, Inderal XL, InnoPran XL 2 class, unselective beta-blocker 60 mg; 10 mg; 20 mg; 40 mg; 80 mg; 120 mg; 160 mg;1 mg / ml; 20 mg / 5 ml; 80 mg / ml; 40 mg / 5 ml; 4.28 mg / ml 7.0 Risk is not excluded Interacts with alcohol
Flecainide Tambocor 1 class 50 mg; 100 mg; 150 mg 4.0 Risk is not excluded -
Lidocaine Anestacaine, DentiPatch, Dilocaine, L-Caine, Lidoject 1, Nervocaine, Truxacaine, UAD Caine, Xylocaine HCl 1 class, local injection anesthetics, 2%; 1%; 1.5%; 1% without preservatives; 0.5%; 4%;7.5% -5%; 20%; 10%; 5% -0.2%; 5% -0.4%; 5% -0.8%;2% without preservatives; 1,5% without preservatives;0,5% without preservatives; 4% without preservatives;5%; hydrochloride; 1% -NaCl 0.9% - No data on risks to the fetus -
Propafenone Rythmol, Rythmol SR 1 class 150 mg; 300 mg; 225 mg; 325 mg; 425 mg 6.0 Risk is not excluded -
Mexiletin Mexitil 1 class 150 mg; 200 mg; 250 mg - Risk is not excluded -
Vasopressin Vasostrict Antidiuretic hormones 20 units / ml; 1 unit / Ml-D5%; 20 units / 100 ml-D5% - Risk is not excluded -
Acebutolol - 2 class of cardioselective beta-blockers 200 mg; 400 mg - No data on risks to the fetus Interacts with alcohol

Drugs in the syndrome of postural tachycardia

To date, there are no randomized trials approved drugs for the treatment of postural tachycardia syndrome (SPT). The purpose of using drugs is to control the symptoms in order to improve the overall physical form. Treatment should be adapted to each patient, taking into account the cause of development of SPT, because the same drugs can have very different effects on different people.

Patients with SPT, as a rule, are very sensitive to medicines and therefore the therapeutic effect begins with tiny doses (even infant doses). Side effects should be carefully monitored. This is often the cause of very deep disappointments for the sufferers, who may need to try many different drugs before finding the right combination.


Drugs that slow the heart rate

  • Beta-blockers
    • Bisoprolol
    • Propranolol
    • Labetalol
    • Metoprolol
  • Iwabradine

Alpha agonists

  • Midodrine. The purpose of using an alpha-agonist is to narrow the blood vessels to direct blood back to the heart.

Selective serotonin reuptake inhibitor

  • Sertraline
  • Escitalopram
  • Citalopram
  • Paroxetine

SSRIs are usually prescribed for the treatment of depression and anxiety disorders, but recently some evidence has emerged that indicates that serotonin plays a role in controlling heart rate and blood pressure. As a result, SSRIs may be useful in the treatment of postural tachycardia.

Inhibitor of serotonin-norepinephrine reuptake

  • Bupropion
  • Venlafaxine
  • Duloxetine

In some cases, inhibitors may worsen tachycardia in patients with postural tachycardia.

Medicines that increase blood volume

Fludrocortisone. It is a synthetic steroid that promotes the preservation of salt in the body and causes an increase in the volume of blood in the blood vessels. It does not have the same side effects as other steroids (such as prednisolone), which often disturb patients. It is necessary to monitor the level of potassium in the blood.

Desmopressin . This hormone, which reduces the production of urine, promotes fluid retention and, consequently, reduces the heart rate, improves symptoms in SPT.

Erythropoietin . This hormone increases the production of red blood cells and subsequently increases the volume of blood. Erythropoietin causes the blood vessels to narrow.

Other medicines

Clonidine, methyldopa. Reduce the heart rate and reduce blood pressure by acting directly on the centers of the brain.

Octreotide . Narrows the blood vessels in the abdominal cavity. Daily injections may be inadequate, but a long-acting form has been developed that can be effective for a week.

Pyridostigmine . Affects the vegetative ganglia of the nervous system, contributing to an increase in the tone of the vagus nerve. This allows you to reduce the heart rate. Side effects may include stomach pain, nausea, diarrhea, which may be unpleasant for some patients.

Modafinil (Modafinil) . This is a stimulant, usually used in some sleep disorders, and can improve alertness and reduce blurred consciousness in some patients with SPT. The drug may enhance tachycardia in some patients, but this effect is not very pronounced.

Doctors have their favorite combination of drugs that can adapt according to the symptoms of patients or concomitant diseases. Fludrocortisone, midodrin, beta-blocker or ivabradine, as a rule, are used initially.

Video: Remedies for heart problems

Preparations that cause tachycardia

Provides a list of medicines that can cause tachycardia (rapid heart rate).

Anagrelide

The drug is used to treat a high level of platelets, formed against the background of bone marrow disease.

The most common side effects are headache, palpitations, diarrhea, weakness, fluid retention, nausea, abdominal pain, dizziness, difficulty breathing, flatulence, vomiting, fever, swelling in the extremities, rash, urticaria, chest pain, loss of appetite, fast pulse, sore throat inflammation, restlessness, tingling, back pain, itching and indigestion.

Aspirin and Oxycodone (Aspirin and Oxycodone)

Anesthetics.

The most common side effects are headache, palpitations, diarrhea, weakness, fluid retention, nausea, abdominal pain, dizziness, difficulty breathing, flatulence, vomiting, fever, swelling in the extremities, rash, urticaria, chest pain, loss of appetite, fast pulse, inflammation of the pharynx, restlessness, tingling, back pain, itching and indigestion

Chlordiazepoxide and clidinium bromide (Chlordiazepoxide and Clidinium Bromide)

The first drug is an anxiolytic drug from the benzodiazepine group, the second is a bronchodilator.

The most common side effects are dry mouth, blurring, indecision and urgency when urinating, constipation, fever, heat stroke, rapid heart rate and pupil dilating

Dosiepin

Combined herbal preparation from the group of antidepressants

The most common side effects are dizziness, blurred vision, rapid heart rate, urine retention, tremor, blood clotting disorder, low blood pressure, sexual dysfunction and sweating

Ephedrine (Ephedrine)

Refers to sympathomimetic drugs.

The most common side effects are nervousness, insomnia, fainting, headache, fast heart rhythm, palpitation and sweating.

Epinephrine (Epinephrine, Adrenaline)

It is a non-glycosidic cardiotonic agent, refers to adrenergic and dopaminergic drugs.

The most common side effects are tremor, weakness, dizziness, sweating, palpitation, pulmonary edema, rapid heart rate, transient or moderate anxiety, anxiety, pallor, nausea, vomiting, headache and / or breathing problems

Epoprostenol (Epoprostenol)

Synthetic prostacyclin, mainly used in primary pulmonary hypertension.

The most common side effects are joint pain, restlessness, dizziness, slow or fast heart rhythm, difficulty breathing, abdominal pain and musculoskeletal pain.

Glyceryl trinitrate (Glyceryl trinitrate)

The drug is used to dilate the blood vessels, that is, it is a vasodilator.

The most common side effects are redness of the face, dizziness, fast heart rhythm, headache.

Moclobemide

Reversible MAO inhibitor (monoamine oxidase).

The most common side effects are dry mouth, headache, insomnia, nausea, dizziness, tremor, agitation, anxiety, constipation, a fast heart rhythm, drowsiness and low blood pressure.

Nalmefene

The drug is an antagonist with a predominant relationship to opioid receptors.

The most common side effects are nausea, dizziness, fever, headache, fast heart rate, high blood pressure, chills, muscle aches, cramps in the abdomen and joint pain

Niacin Er and Simvastatin (Niacin Er and Simvastatin)

Antihyperlipidemic combined preparations.

The most common side effects are dizziness, fainting, fast heart rhythm, palpitation, shortness of breath, sweating, burning sensation, chills, fluid retention.

Niacin (Extended Release) and Lovastatin (Lovastatin)

Medications are used to treat atherosclerosis.

The most common side effects are dizziness, fainting, fast heart rate, heart palpitations, shortness of breath, sweating, burning sensation, chills and / or swelling.

Nicardipine

Calcium channel blocker, dihydropyridine derivative.

The most common side effects are low blood pressure and a fast heart rate.

Oprelvekin (Oprelvekin)

It is used to treat thrombocytopenia.

The most common side effects are fluid retention, shortness of breath, rapid heart rate, palpitations, abnormal heart rhythm and lung infection

Paliperidone Palmitrate (Paliperidone Palmitrate)

Refers to neuroleptics, antipsychotic drugs.

The most common side effects are additional pyramidal symptoms, fast heart rhythm, internal anxiety, drowsiness, indigestion, constipation, weight gain and nasopharyngeal inflammation.

Phenoxybenzamine

A means of treating pheochroocytoma, accompanied by high blood pressure and excessive sweating.

The most common side effects are low blood pressure, fast heart rate, inhibition of ejaculation, nasal congestion and miosis.

Folotin (Pralatrexate Solution)

An antitumor agent used to treat Hodgkin's lymphoma.

The most common side effects are a decrease in the number of platelets and leukocytes, inflammation of the mucosa, nausea, fatigue, anemia, constipation, fever, fluid retention, coughing, nosebleeds, vomiting, diarrhea, difficulty breathing, loss of appetite, rash, itching, sore throat , abnormal liver function abnormally, abdominal pain, pain in the limbs, back pain, night sweats, weakness, rapid pulse.

Pralidoxime

Reactivator of the enzyme acetylcholinesterase.

The most common side effects are blurred vision, double vision, blurred vision, dizziness, headache, drowsiness, nausea, muscle weakness and a fast heart rate.

Voriconazole (Voriconazole)

Antifungal agent, a derivative of triazole.

The most common side effects are visual disturbances, fever, nausea, rash, vomiting, chills, headache, abnormal liver function, rapid heart rate and hallucinations.

Video: Tablet. Tachycardia. Ether from 23.03.2016. HD version


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