Ascorbic acid is an application in cardiovascular diseases

Author Ольга Кияница

2019-02-01

The human body needs many nutrients that allow normal functioning of all organs and tissues. One of the most necessary is vitamin C. Its proper use helps prevent the development of various diseases, and, if necessary, help cure certain cardiovascular disorders.

Ascorbic acid (vitamin C) is a water-soluble vitamin that is found in many foods, but most of it in citrus fruits. Also today in pharmacies, many dietary supplements are offered, which can also compensate to some extent the lack of this vitamin.

Vitamin C is mainly used for the treatment of scurvy, but in some cases it is quite effective in the prevention and treatment of cardiovascular diseases.

Vitamin C refers to those nutrients that take direct part in the metabolism. Ascorbic acid is an antioxidant, it also supports the functioning of the immune system. Mostly, the nutrient is taken orally in the form of tablets, but if necessary, it is used for injection.

Video: Vitamin C, An Important Factor in Cardiovascular Health

Application of ascorbic acid in dragee with the capillary fragility

In cases of vitamin C deficiency, the fragility of capillaries increases, especially in the elderly and people with diabetes mellitus.

The severe deficiency of vitamin C (scurvy) is a generally recognized but rare cause of increased fragility of capillaries.Can vitamin C supplementation help the fragility of capillaries in people who do not have scurvy, is not fully understood.

Patients on dialysis may experience a decrease in vitamin C levels, which can lead to fragility of capillaries. In one study, patients receiving dialysis, 50 mg of vitamin C per day had no effect on capillaries. It is also indicated that people with renal insufficiency and those undergoing dialysis should not take more than 100 mg per day.

According to preliminary studies, vitamin C can reduce the capillary weakness of diabetics who often have low levels of vitamin C in the blood compared to non-diabetics. In a double blind study, elderly people with low vitamin C levels and fragility of capillaries were assisted with the addition of one gram of vitamin C per day.

Ascorbic acid: instructions for use in high-cholesterol dragee

Vitamin C, apparently, protects the vessels from damage by low density lipoprotein (LDL cholesterol). In some studies, cholesterol levels were reduced when taking ascorbic acid.

Vitamin C reduces LDL cholesterol damage. In some clinical trials, cholesterol levels have been lowered when people with elevated cholesterol have been using vitamin C supplements. Some studies have reported that a reduction in total cholesterol occurs precisely by reducing LDL cholesterol.

Doctors generally recommend taking 1g of vitamin C. At the same time, an overview of isolated research on vitamin C and heart disease has shown that most of the protection against heart disease with vitamin C is most likely achieved when taking only 100 mg of ascorbic acid acids per day. More detailed instructions should be provided by the attending physician to the particular patient.

Video: Cardiovascular disease and vitamin C (Dr. Rath Foundation)

Ascorbic acid: instructions for use in pills with atherosclerosis

Supplementation of the main treatment with vitamin C can help stop the progression of atherosclerosis and prevent the development of serious heart disease.

The experimental increase in the level of homocysteine ​​led to temporary dysfunction of cells lining the blood vessels.Researchers are concerned that this dysfunction may be associated with atherosclerosis and heart disease. One controlled study reported that vitamin C reversed dysfunction caused by an increase in homocysteine ​​levels. Vitamin C also normalizes the level of LDL.

Despite the protective mechanisms attributed to vitamin C, some studies failed to link the consumption of the substance with protection from heart disease. These negative tests were mainly conducted using people who consume 90 mg of vitamin C per day or more - a level at which further normalization of LDL levels may not occur.

Studies of people who eat foods that contain less vitamin C could show the link between dietary vitamin C and cardiovascular disease. Therefore, leading vitamin C researchers have begun to assume that vitamin C can play an important role in the prevention of cardiovascular disease, but only when using 100-200 mg per day.

In a double-blind study, 250 mg of vitamin C was slowly released twice a day for three years. As a result, the progression of atherosclerosis slowed down by 15% compared with the control group. Many doctors assume that people take vitamin C - often 1 gram (1000 mg) per day - despite the fact that studies do not yet confirm the efficacy of a dose of above 500 mg per day.

Ascorbic acid: a method for use in arterial hypertension

Some doctors recommend that patients with arterial hypertension take vitamin C, which has been found to have an effect of lowering blood pressure.

In 29 randomized controlled trials, the addition of vitamin C in comparison resulted in a statistically significant decrease in systolic blood pressure (average of 3.84 mm Hg) and diastolic (mean 1.48 mm Hg) blood pressure.

The mean reduction in blood pressure in studies that included only people with hypertension was 4.85 mm Hg. for systolic and 1.67 mm Hg for diastolic blood pressure. Thus, vitamin C, when it is administered in moderate amounts (for example, 500 mg per day), has a moderate effect on lowering blood pressure, both in people with severe hypertension and in the determination of normal blood pressure.

Ascorbic acid: indications for use in heart attacks

There is evidence that vitamin C protects blood vessels from problems associated with the risk of heart attack in various ways. However, there is no unambiguous certainty associated with the amount of vitamin C consumed.

The true or borderline deficiency of ascorbic acid appears to increase the risk of heart attacks. However, in studies comparing acceptable (that is, non-deficient) levels with even higher amounts, additional vitamin C supplementation was not effective.

As a result, although many doctors recommend that people at high risk of heart attack take vitamin C - often 1 gram a day - most of the data currently indicate that a sufficient dose may be 100-200 mg of vitamin C per day with food or vitamin supplements.

Conclusion

Vitamin C, or ascorbic acid, has a particularly effective effect on the general health of the person and contributes to the prevention of various diseases of the heart and blood vessels. The dose of ascorbic acid depends on the particular disease and other factors, therefore, medicines containing vitamin C should only be done according to the medical recommendation.

Video: Side Effects Of Taking Too Much Vitamin C


Source

1. Vitamin C https://www.mayoclinic.org/drugs-supplements-vitamin-c/art-20363932
2. Аскорбиновая кислота
3. Аскорбиновая Кислота-Здоровье: состав, показания, дозировка, побочные эффекты https://www.obozrevatel.com/health/lekarstva/askorbinovaya-kislota-zdorove.htm

 


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