Corvalation 0.1 g capsule № 30

Corvalense

Composition of the medicinal product:

active substance: a solution of menthol in the menthyl ether of isovaleric acid;
1 capsule contains 100 mg (0.1 g) of a solution of menthol in an isovaleric acid menthyl ester.
excipients: gelatin capsule shell (gelatin, glycerin, methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216)).

Dosage form.

Capsules are soft.
Soft gelatin capsules spherical or spherical, with a seam, colorless or from slightly yellow to light brownish yellow, filled with a transparent, colorless or yellowish tinge oily liquid with a smell of menthol.

Pharmacotherapeutic group.

Combined cardiological means. The code of the automatic telephone exchange С01Е Х.
The drug exhibits a moderate vasodilator (coronarolytic) effect by reflex stimulation of sensory nerve ("cold") receptors of the oral mucosa and has a calming effect on the central nervous system. Stimulation of receptors is accompanied by the induction of release of endorphins, enkephalins, dinorphins and other opioid peptides that play an important role in reducing pain, normalizing vascular permeability, and regulating other important mechanisms of cardiovascular and nervous system functioning. Under the influence of the drug, physiologically active compounds are released - histamine, kinin, etc.
With sublingual administration, the drug is absorbed from the oral mucosa. The therapeutic effect occurs in about 5 minutes.
After absorption, the drug is biotransformed in the liver and excreted in the urine in the form of glucuronides.

Indications for use.

Light attacks of angina pectoris, neurosis, hysteria, and also as an antiemetic for sea and air sickness, a headache associated with the use of nitrates.

Contraindications.

Hypersensitivity to the drug components, acute myocardial infarction, acute disorders of cerebral circulation, severe arterial hypotension, children's age.

Appropriate safety measures when used.

The drug should not be used for severe attacks of angina pectoris. The drug does not contain sugar and can be used for patients with diabetes mellitus.

Special caveats.

Use during pregnancy or lactation. The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the doctor, the expected therapeutic effect exceeds the possible risk to the fetus / child.

The ability to influence the reaction rate when driving or working with other machinery. Care must be taken in the first hours after taking the drug when driving vehicles or work requiring attention, due to possible side effects (dizziness and drowsiness).

Children. The experience of the drug in childhood is not.

Method of administration and dose.

Corvalation is taken under the tongue. The capsule is kept under the tongue until it is completely dissolved. To accelerate the effect, you can crush the capsule with your teeth.
The frequency of taking the drug depends on the frequency of attacks of angina pectoris. When seizures take 1 capsule under the tongue. If it is necessary to treat angina and other conditions, the maximum daily dose of the drug can be 6 capsules (600 mg) per day. Duration of treatment - up to 7 days.

Overdose.

Symptoms: headache, nausea, agitation, lowering blood pressure, suppressing the central nervous system, impaired cardiac activity, hypersensitivity reactions (angioedema, hives, itching, rash).
Treatment: discontinuation of the drug, symptomatic therapy.

Side effects.

In isolated cases, nausea, discomfort in the abdomen, lacrimation, dizziness are possible. With prolonged use - short-term arterial hypotension, drowsiness. These phenomena are short-lived, pass by themselves. Perhaps the development of allergic reactions, including angioedema, rash, itching.

Interaction with other drugs and other types of interactions.

It is allowed to use Corvalament in combination with preparations that improve metabolic processes (vitamins, asparks, riboxin). The drug can enhance the effect of antihypertensive drugs with simultaneous application.
May enhance the sedative effect of psychotropic drugs, opioid analgesics, alcohol and anesthesia. Simultaneous use with neurotropic drugs, which depress the central nervous system, causes drowsiness.

Shelf life.

2 years.

Storage conditions.

Store in the original packaging at a temperature of 5 ° C to 25 ° C. Keep out of the reach of children.

Packaging.

10 capsules in blisters. 10 capsules per blister; 3 blisters per pack.

Category of vacation.

Without recipe.