Kapikor 180 mg / 60 mg capsule number 60

Author Ольга Кияница


Amount in a package 60
Product form Capsules
Manufacturer Olainfarm JSC (Latvia, Olaine)
Registration certificate UA/12399/01/01
The main medicament Capicor
morion code 200601

Kapikor (CAPICOR) user manual


active substances: meldonia dihydrate (meldonium), gamma-butyrobetaine dihydrate; 1 capsule contains meldonium dihydrate ─ 180 mg, gamma-butyrobetaine dihydrate 60 mg;
auxiliary substances: hydroxypropylcellulose is low-fat, potato starch, silicon dioxide colloidal anhydrous, sodium stearyl fumarate.

Dosage form


Pharmacotherapeutic group

Cardiac preparations, combination. The code of automatic telephone exchange С01Е В20.


As part of complex therapy.

Ischemic heart disease (angina pectoris, myocardial infarction, ischemic cardiomyopathy, post-infarction cardiosclerosis). Chronic heart failure.

Dyshormonal cardiomyopathy.

Acute and chronic disorders of cerebral circulation (cerebral stroke, discirculatory encephalopathy, cerebrovascular insufficiency).

Cardiopsychoneurosis; vegetovascular dysfunction.


Hypersensitivity to the drug and its components.

Increase in intracranial pressure (with violation of venous outflow, intracranial tumors).

Organic lesions of the central nervous system (CNS).

Dosing and Administration

Adults are appointed inside, regardless of food intake.

In the complex therapy ─ 2 capsules 1-3 times a day. The course of treatment is from 2 to 6 weeks.

The maximum daily dose is 6 capsules.

Repeated courses (usually 2-3 times a year) are possible after consultation with a doctor.

For the possible development of a stimulating effect, the last administration of the drug is recommended no later than 3-4 hours before bedtime.

Adverse Reactions

The drug is classified as a V class toxicity.

From the immune system: rarely - allergic reactions (reddening of the skin, skin rash, itching, swelling).

From the side of the central nervous system: rarely - arousal.

From the cardiovascular system: rarely - tachycardia, changes in blood pressure, arrhythmia.

From the side of the digestive tract: rarely - dyspeptic phenomena.


Cases of overdose are not known. In case of an overdose, symptomatic therapy.

Use during pregnancy or lactation

Safety of use Kapikora during pregnancy is not proven. To prevent possible negative effects on the fetus during pregnancy, the drug is not prescribed.

It is not revealed, Kapikor is excreted into breast milk. If Kapikor's treatment for the mother is necessary, then the lactation is terminated.


The use of the drug for children is contraindicated.

Application features

The drug is used with caution in chronic liver and kidney diseases.

For the possible development of a stimulating effect, the last administration of the drug is recommended no later than 3-4 hours before bedtime.

The ability to influence the reaction rate when driving or working with other machinery

There is no evidence of a negative effect of the drug on the reaction rate when driving vehicles or working with other mechanisms.

Interaction with other drugs and other interactions

Strengthens the therapeutic effects of blockers of β-adrenoreceptors, cardiac glycosides, certain antihypertensive drugs.It is also possible to use antianginal drugs, anticoagulants, antiaggregants, antiarrhythmics, diuretics, bronchodilators.

Pharmacological properties

Pharmacodynamics. Kapikor is a complex drug whose therapeutic effects are caused by a combination of two active components:

  • meldonia dihydrate;
  • gamma-butyrobetaine dihydrate.

This combination provides a powerful and rapid cardio - and cerebroprotective action to Kapikor, eliminating the dependence of the rate of onset of therapeutic effects on body exhaustion under conditions of ischemia and stress of various genesis (oxidative including).

Gamma-butyrobetaine dihydrate enhances the effect of Kapikora, acting on the induction of NO biosynthesis, protects cells from the toxic effects of free radicals, normalizes oxidative homeostasis at the cellular level, positively affects endothelial function.

Meldonium dihydrate inhibits the transport of long chain fatty acids and their metabolites in the mitochondria, due to a decrease in the biosynthesis of carnitine, which preserves the aerobic pathway of metabolism in conditions of tissue hypoxia, prevents the depletion of ATP and creatine phosphate in cells, accumulation of lactic acid and the emergence of cellular acidosis, disruption of enzymatic processes and dysfunction ion channels and also with it has a certain effect on the increase in the concentration in the body of gamma-butyrobetaine dihydrate.

These aggregate mechanisms provide an optimal level of gamma-butyrobetaine dihydrate, which causes more pronounced and rapid NO-dependent effects: vasodilatous, antiplatelet, anticoagulant, antioxidant and others; affects the regulation of apoptosis and proliferation, maintenance of vascular homeostasis and others.

The drug shows antiischemic, cerebro, cardioprotective and immunocorrective effects.

With heart failure, Kapikor improves the contractility of the myocardium, increases tolerance to physical exertion; with stable angina II and III functional class reduces the incidence of heart attacks; provides a moderate hypotensive effect and normalizes the rhythm of cardiac contractions.

With vascular lesions of the brain, Kapikor improves cerebral hemodynamics, normalizes metabolism in nerve cells, optimizes oxygen consumption by brain tissue, thereby achieving the effect of improving cognitive functions, mental and physical activity, normalizing the psychoemotional state, and reducing the feeling of overwork.

Pharmacokinetics. After oral administration, the drug is rapidly absorbed from the digestive tract. Its bioavailability is 78%. The maximum concentration in the blood plasma is achieved in 1-2 hours after administration. Metabolized in the body with the formation of two major metabolites, which are excreted by the kidneys. The half-life is 3-6 hours.

Basic physical and chemical properties:

solid transparent / transparent or white / white No. 0 capsules of hydroxypropylmethylcellulose (HPMC) containing white or almost white powder.

The presence of granules and conglomerates of particles is allowed.

Shelf life

3 years.

Storage conditions

Store in a dry, dark place at a temperature of no higher than 25 oC. Keep out of the reach of children.


10 capsules per blister; 2 or 6 blisters in a pack of cardboard.

Category of leave

On prescription.

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