Hemorrhoid Ointment 57g

HEMORRON instructions for use

Composition

active ingredients : phenylephrine hydrochloride, shark liver fat (vitamin A)
1 g of the ointment contains phenylephrine hydrochloride 2.5 mg, shark liver fat (vitamin A) 30.0 mg (500 IU)
auxiliary substances : petrolatum (petroleum jelly), mineral oil, lanolin, wax white, paraffin, microcrystalline wax, lanolin alcohol, purified water, glycerin, corn oil, methylparaben (E 218), propylparaben (E 216), benzoic acid (E 210) , butylhydroxyanisole (E 320), tocopherol (vitamin E), thyme oil.

Dosage form

Ointment for external and rectal administration.
Homogeneous transparent yellowish oily ointment with the smell of fish oil.

Pharmacological group

Means for the treatment of hemorrhoids and anal fissures for topical application.

The code of automatic telephone exchange С05А Х03.

Combined drug, the effect of which is due to the properties of its constituents, promotes resorption of hemorrhoids and provides a rapid elimination of painful burning, itching and other discomfort phenomena inside and outside the anus.

Fat shark liver (vitamin A) has a pronounced anti-inflammatory, hemostatic action, stimulates reparative processes, promotes healing of wounds and microcracks.

Phenylephrine hydrochloride - alpha-adrenomimetic, has a local vasoconstrictive effect, reduces edema, itching, normalizes the relationship between the influx and outflow of blood in the cavernous corpuscles of the rectum.

The effect of the drug comes very quickly after its application and lasts from 30 minutes to 4:00. The metabolism of the drug that enters the general bloodstream occurs in the liver. It is excreted by the kidneys and with feces.

Indications

Hemorrhoids, accompanied by symptoms of burning, itching, a sense of discomfort.

Contraindications

Hypersensitivity to the drug components, significant arterial hypertension, tachyarrhythmia, cardiac conduction disorder, decompensated heart failure, severe renal and hepatic insufficiency, thyrotoxicosis, acute pancreatitis, concomitant use with MAO inhibitors or within 15 days after discontinuation of treatment with MAO inhibitors, thromboembolic disease, granulocytopenia.

Appropriate safety measures for use

Do not exceed the dose specified in the instructions. Do not use the applicator if it causes pain or if bleeding occurs after applying the drug. The drug should be used with caution for patients with hypertension, cardiovascular diseases, thyroid diseases, zakratougolnoy glaucoma, diabetes. With hepatitis, urination disorders, the use of the drug is permissible taking into account the risk / benefit ratio that the doctor determines.

Special caveats

In the case of copious bloody discharge from the anus or the presence of symptoms of the disease for 7 days of treatment, it is necessary to consult an additional doctor.

Use during pregnancy and lactation

The use of the drug during pregnancy, breast-feeding, is possible in the case when, according to the doctor, the benefit to the mother exceeds the potential risk to the fetus.

The ability to influence the reaction rate when driving vehicles or other mechanisms

There are currently no messages. However, when managing vehicles or other mechanisms, it is recommended that special care be taken, taking into account the possibility of developing adverse reactions from the nervous system.

Children

It is not recommended for children under 12 years.

Dosing and Administration

The drug is applied externally and intraperitoneally by adults and children over 12 years of age.

External application. Rinse and drain the areas affected by hemorrhoids with a napkin or toilet paper, apply a thin layer of ointment. Apply in the morning, before going to bed and after defecation up to 4 times a day.

Intraperior rectal application. Remove the protective cover from the applicator. Put the applicator on the thread of the tube head with the ointment. Squeeze out some of the ointment to fill the applicator. Well lubricate the applicator with ointment and gently insert it into the anus. Pressing on the tube, squeeze the ointment from the applicator, remove the applicator and apply a thin layer of ointment on the skin around the anus. After each use, the applicator should be thoroughly cleaned and closed with a protective cover.

Regular use of the drug ensures the elimination of symptoms of the disease. There are no restrictions on the duration of application, but if the condition does not improve after 7 days, treatment should be discontinued.

Overdose.

When applying ointment, no overdose was observed. However, overdose may increase the manifestations of adverse reactions, especially with prolonged use. Arterial hypertension, pain and discomfort in the heart, palpitation, dyspnea, noncardiogenic pulmonary edema, agitation, convulsions, sleep disturbance, anxiety, irritability, psychoses with hallucinations, weakness, anorexia, nausea, vomiting, oliguria, urinary retention, redness of the face can be observed. , sensation of coldness in the extremities, paresthesia, hypersensitivity, hyperglycemia, hypokalemia, reduction of blood flow to vital organs, which can lead to deterioration of blood supply to the kidneys, metabolic acidosis , an increase in the load on the heart due to an increase in the overall resistance of peripheral vessels.

Treatment is symptomatic. In cases of significant excess of recommended single and daily doses, there may be a tendency to hypercoagulable.

Side effects

This drug is usually well tolerated, but there may be side effects caused by phenylephrine hydrochloride.

From the side of the cardiovascular system: reflex bradycardia, arrhythmia, cardiac rhythm disturbances, increased blood pressure, flushes of blood to the face.
On the part of the immune system: allergic reactions, including cross reactions when allergic to other sympathomimetics, which can manifest as a rash, itching, angioedema, contact dermatitis.
From the nervous system: dizziness, nervousness, headache, tremor, insomnia, a sense of fear.
At the site of application, there may be hyperemia, rash, itching, swelling, mild pain / burning if damaged or bleeding from the anus.

Interaction with other drugs and other interactions

Do not use together with other vasoconstrictors in any route of administration of the latter, as well as with β-adrenoblockers, simultaneous intake of which can lead to hypertension and excessive bradycardia with possible cardiac blockade.

Atropine sulfate blocks reflex bradycardia and increases the vasopressor effect caused by phenylephrine.

It should be used with thyroid hormones, preparations that affect cardiac conduction (cardiac glycosides, antiarrhythmic drugs).

When used with drugs that excrete potassium (diuretics such as furosemide), it is possible to increase hypokalemia and reduce arterial sensitivity to phenylephrine.

Simultaneous reception with other sympathomimetics can lead to additional stimulation of the central nervous system to an extremely high level, accompanied by irritability, insomnia, convulsions.

Shelf life

4 years.
Do not use after the expiration date stated on the package.

Storage conditions

Store in a place inaccessible to children at a temperature not exceeding 25 ° C.

Packaging

For 57 g in a tube, 1 tube with an applicator in a cardboard box.

Category of leave

Without recipe.