Cerebral vascular aneurysm

Author Ольга Кияница

2018-11-07

Vascular diseases are directly related to trophic disorders. If the pathology concerns the brain, then the tissues primarily suffer from a lack of oxygen, which can lead to serious disturbances and even death of the patient. Therefore, in case of a disease by the type of aneurysm of the cerebral vessels, a qualitative diagnosis and appropriate treatment are of key importance.

Cerebral vascular aneurysm (ASGM) is a cerebrovascular disorder that usually develops after a stroke. The likelihood of ASGM increases with poor control of hypertension and unhealthy lifestyles.

Aneurysms of cerebral vessels are dangerous due to the possibility of rupture, as a result of which hemorrhage can occur, inside the brain and into the subarachnoid space. Such complications lead to the death of the patient or persistent neurological disorders.

To prevent such consequences of the aneurysm, early diagnosis should be carried out. With timely detection of pathological expansion of the vessel, it is “disconnected” from the bloodstream, for which endovascular occlusion or “clipping” is performed.

Video: Medicine. What is a cerebral aneurysm?

Description of a brain aneurysm

Brain aneurysm, also known as cerebral aneurysm or intracranial aneurysm, is an abnormal expansion of a blood vessel in the brain. It is asymptomatic for many years. It is a life-threatening condition and therefore requires immediate medical attention. There are two types of aneurysms, depending on the form of expansion.

  1. Bagular: a common type of brain aneurysm and the most common cause of subarachnoid hemorrhage. Look like bag-shaped formations.
  2. Spindly: not very common. In this pathology, the blood vessel bulges in all directions, forming an aneurysm in the form of a spindle.

Also found is a mixed form of bag-shaped and spindle-shaped aneurysm and pseudo-aneurysm.

Additionally, cerebral vascular aneurysms are divided according to the following characteristics:

  • By the number of cameras available in the aneurysm - multi-and single-chamber.
  • By value: billionths (not more than 3 mm), usual (from 4 to 15 mm), large size (from 16 to 25 mm) and gigantic (26 mm and more).
  • Location: most often, in 45% of cases, the pathological expansion of the anterior cerebral artery occurs, in 26% of the internal carotid artery, in 25% of the middle cerebral artery, in 4% of the arteries of the vertebro-basilar system.

Aneurysms are multiple, that is, there is an expansion of two or more vessels. Such a violation occurs in 15% of cases.

ACGM relatively common. Approximately 10–12 million people in the United States have brain aneurysms, and about 27,000 new aneurysms are detected each year (Brisman, Song & Newell, 2006).

The ICG-10 ASGM is classified in the “Other forms of aneurysm and dissection (I72)” class. Here, the following types of aneurysm are defined under separate codes:

  • cerebral (without rupture) (I67.1);
  • torn (I60).

Aneurysms on the blood vessels located in the posterior half of the brain (vertebral arteries, basilar artery and posterior communication artery) have a higher risk of bleeding than aneurysms found on the blood vessels in the anterior half of the brain (carotid artery, middle cerebral artery and anterior cerebral artery ).

Causes of brain aneurysm

ACGM are acquired and congenital. The last type of aneurysm occurs in the process of fetal development, when anomalous formation is formed. Acquired aneurysm is the result of the influence of predisposing factors against the background of predisposing conditions.

Overtime, for example, can contribute to arterial wall wear due to increased blood pressure. The thinned part of the vessel wall gradually expands against the background of an increase in the size of the artery.

In such cases, the weakened wall bulges outward, leading to aneurysm. Also, due to persistent high blood pressure, an abnormal vessel can rupture and cause bleeding in the brain. This leads to cerebrovascular or hemorrhagic stroke.

Risk factors for the development of ASGM

Cerebrovascular aneurysms are most often defined between the ages of 40 and 60 years. Women are more prone to this pathology than men. Other predisposing factors include:

  1. Smoking.
  2. High blood pressure or hypertension.
  3. Genetic predisposition.
  4. The presence of arteriovenous malformation.
  5. Severe head injury.
  6. The presence of tumor formations.
  7. Alcohol and drug abuse.
  8. Polycystic kidney disease.
  9. Marfan syndrome.

Factors that are thought to increase the likelihood of aneurysm rupture include its rapid growth, multiple lesions, a rupture of a previous aneurysm, symptoms of aneurysm hemorrhage, or nerve compression. They also include irregular autoimmune disorders of the aneurysm and familial susceptibility to aneurysm ruptures (which confirms the presence of this complication in several family members).

Symptoms of brain aneurysm

Brain aneurysms cause symptoms only when they break. However, intact aneurysms can also provoke the development of a clinical picture, especially when the aneurysm is large or squeezes along with the passing nerves and tissues.

Common features include:

  1. Headache.
  2. The pain is inside or behind the eyes.
  3. Difficulties in speaking.
  4. Changes in vision.

Symptoms of aneurysm rupture are characterized by an abrupt onset in a relatively short time. They differ in the location of the aneurysm. In particular, it may be noted:

  1. Sudden, severe headache.
  2. Pain in the neck.
  3. Photosensitivity (sensitivity to light).
  4. Fainting (loss of consciousness).
  5. Disorder of consciousness.
  6. Nausea and vomiting.
  7. Difficulty with speech.
  8. Sudden weakness and numbness.
  9. Seizures convulsions.

Abnormal drowsiness, dilated pupils (or only on one side) may also be detected .

Complications of brain aneurysm

When the aneurysm is broken, it causes bleeding in the brain or a so-called hemorrhagic stroke. This leads to oxygen deprivation and blood supply to the brain tissue, which in turn causes ischemia. Myocardial ischemia can also occur in some cases.

There is a possibility of re-bleeding from the aneurysm if the pathology is not treated quickly.

Hydrocephalus (accumulation of cerebrospinal fluid in the brain) can occur when blood enters the subarachnoid space through a ruptured vessel.

In severe cases, the brain gradually loses its function, resulting in a coma and, ultimately, death.

Diagnosis of brain aneurysm

Screening tests help identify the aneurysm at the stage of its rupture. However, if symptoms of cerebral disorder do occur, a neurosurgeon may recommend studies to confirm the diagnosis. The following diagnostic methods are commonly used:

  • Computed tomography (CT) . This study is based on the use of x-rays, which are used to produce images. In this case, before the test, an injection of an anodine-based contrast agent is injected. Contrast helps in a detailed view of the structures of the brain.
  • Magnetic resonance imaging (MRI) . In this test, magnetic waves are used to create images. They provide images with higher resolution than CT.

Video: MRI of cerebral vessels

  • Examination of cerebrospinal fluid . To obtain cerebrospinal fluid, a lumbar puncture is made, after which the resulting biological material is examined for the presence of blood. This test is performed if bleeding into the subarachnoid space is suspected.
  • Cerebral angiography (CAG). This is an invasive study, which is resorted to in the case of the ineffectiveness of other diagnostic methods. CAG provides sufficient results to determine the size and location of the aneurysm. During this test, a thin flexible tube is inserted into the inguinal artery and guided through the vessels to the brain. Then the dye is injected through the tube to visualize the brain and obtain images.

Figures 2a and 2b: a side view of a ruptured aneurysm of the left posterior artery (indicated by an arrow) on the cerebral angiogram before the treatment of the aneurysm. Figure 2c: after treatment with coiling aneurysm.

Treatment of brain aneurysm

Treatment depends on the patient's age, general health, size, shape, and location of the aneurysm. The treatment approach differs between controlled, uncontrolled and ruptured aneurysms.

In any case, the patient’s condition should be monitored, but special care is required in determining the uncontrolled aneurysm, which is immune to therapy. Treatment in such cases can be targeted to the main predisposing factors that increase the risk of rupture, for example, hypertension.

The main groups of drugs used before surgery:

  • Antihypertensive drugs that are prescribed for the treatment of high blood pressure.
  • Acetaminophen-type NSAIDs (nonsteroidal anti-inflammatory drugs) can be used to relieve headaches.
  • Anti-epileptic drugs such as levetiracetam and phenytoin are prescribed to prevent seizures.

Surgical treatment of aneurysms

Arterial aneurysm clipping . In this procedure, anesthesia is made and an incision is made on the skull to remove the bone graft. It provides access to the aneurysm. When pathological formation is detected, a metal bracket is used to completely close the aneurysm. This procedure is often accompanied by the loss of sufficient blood.

Flow redirection stents. With the help of a special device - a stent, that is, a thin mesh tube - an outlet for blood flow from the aneurysm area is made. Changing the local blood circulation gives enough time to heal the aneurysm and develop a new blood vessel in the affected area.

Endovascular coiling. During this procedure with the participation of a thin catheter inserted into the inguinal artery and sent to the brain, the aneurysm is wrapped. For this, a small platinum wire is used, which is delivered to the injured site through a catheter. It is with its help that the aneurysm is sealed. This prevents the rupture of the pathological formation.

In case of aneurysm rupture, nimodipine is prescribed as immediate medical care to reduce the risk of traumatic brain injury due to bleeding.

If, after the treatment of the aneurysm, there is such a consequence as a stroke, then there may be weakness in the limbs and difficulty in speaking. In such cases, counseling a physiotherapist and a speech therapist is necessary, followed by practical exercises that help overcome these problems.

Prognosis for brain aneurysm

The prognostic conclusion in each specific case is individual and depends on the size of the aneurysm, as well as its location, age of the person, general health and neurological condition. Small aneurysms (less than 7 mm) have a low risk of rupture and slowly increase. (As a rule, in such cases the risk of rupture is less than one percent.)

Some people with a torn cerebral aneurysm die from initial bleeding. Other patients with cerebral aneurysm recover with a small or severe neurological deficit. The most significant factors in determining the result is the assessment on the scale of Hunt-Hess (Hunt & Hess), as well as the age of the patient.

Usually, patients with bleeding from the Hunt & Hess I and II degree when entering the emergency room and patients younger than the typical age range of vulnerability (up to 40 years), are given a good prognosis with a low probability of death or permanent disability. Elderly patients and patients with a lower degree of Hunt & Hess at admission give a poor prognosis. As a rule, in two thirds of such cases, a bad outcome, death or permanent disability is determined.

Preventing Brain Aneurysm

If a high risk of developing an aneurysm of cerebral vessels is determined, you must first seek the advice of a neurologist and follow them properly, as well as make some changes in lifestyle.

In particular, you need:

  1. Perform regular exercise regularly.
  2. Make a diet of healthy and healthy foods.
  3. Take medication prescribed by your doctor in the correct order. If there is hypertension or any other disease that increases the risk of aneurysm, you need to be especially serious about taking the right medications.
  4. Blood pressure should be monitored regularly.
  5. Stop smoking.
  6. Give up alcohol.

If possible, pass screening tests, especially in the presence of unfavorable heredity or congenital disorders that can cause aneurysm.

Video: Treatment of brain aneurysm in Israel. Embolization


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